Internazionale centre-half Stefan de Vrij and Feyenoord left-back Quilindschy Hartman are the latest withdrawals from the Netherlands squad through injury as they prepare to host Scotland in Friday’s friendly.

Forwards Brian Brobbey and Joshua Zirkzee, midfielder Frenkie de Jong and defenders Micky van de Ven and Sven Botman were already missing, with 33-year-old Al-Ettifaq midfielder Georginio Wijnaldum drafted back into the national set-up after an absence of nine months.

Scotland have also lost two central defenders after FC Copenhagen’s Scott McKenna followed Norwich City’s Grant Hanley in being ruled out this week.

They join midfielder Callum McGregor, full-back Aaron Hickey and forward Jacob Brown on the list of unavailable players.